Recurrent Pregnancy Loss & Miscarriage

What is Recurrent Pregnancy Loss?

Recurrent pregnancy loss (recurrent miscarriage) affects approximately 5 percent of all reproductive age couples and is typically defined as having at least two consecutive miscarriages or three total over a woman’s individual reproductive history.

Causes of Miscarriage

There are many possible causes of recurrent pregnancy loss including the following:

  • Genetic causes
  • Uterine causes
  • Ovarian causes
  • Male factor causes
  • Immunologic causes
  • Blood clotting disorders
  • Hormonal deficiencies

Our doctors use evidence-based medicine to diagnose and treat recurrent pregnancy loss.


The evaluation of recurrent pregnancy loss typically involves one or more of the following tests:

  • A transvaginal ultrasound to evaluate the uterus to rule out uterine fibroids
  • hysterosalpingogram to rule out a uterine septum
  • Ovarian reserve testing to look for a decreased number or decreased quality of eggs in the ovaries.
  • Hormone testing on the third day of your menstrual cycle looking specifically at FSH, LH and estradiol
  • Additional hormone testing may include prolactin and thyroid tests

We may also check for autoimmune problems such as antiphospholipid antibodies, a common cause of recurrent pregnancy loss that can be treated with a combination of aspirin and heparin. As long as your medical history is normal without a history of prior blood clots, further blood clot testing is not recommended.

A rare cause of recurrent pregnancy loss takes place when a man or woman has an underlying genetic abnormality resulting in a rearrangement of their chromosomes and abnormal eggs or sperm which can result in abnormal embryos. These abnormal embryos have a higher chance of miscarriage. Blood work can determine if there is any evidence of a genetic abnormality causing the recurrent pregnancy loss.

Treatment Options

Because miscarriages are so emotionally involved, patients frequently become determined to enter into any form of treatment which could theoretically improve their pregnancy rates. Our goal is to first help you identify the most likely causes for your recurrent pregnancy loss and explore treatment options that provide you a high chance of having a healthy pregnancy with a low chance of harm.

Progesterone replacement is frequently administered to help treat any progesterone deficiencies that a woman may have in her luteal phase – often referred to as a luteal phase defect.

Make an Appointment with us

If you have questions about recurrent miscarriage or would like further evaluation, we encourage you to contact us to schedule a new patient appointment.

During your new patient visit we will review your prior medical records and prior test results, if any. We will go over a detailed history of your miscarriages including when they occurred, how far along you were when you had the miscarriage(s) and whether or not you were on any medication treatment at that time.

Call us Today!

Here at Coastal Fertility Specialists we have the ability to diagnose and treat many causes of recurrent pregnancy loss. We will do everything we can to investigate the causes of your fertility problems and help you bring home a baby.  Call us at 843-883-5800 for any  questions or to schedule an appointment.